I cannot agree more. I cringe every time I see someone changing a tire on the side of a highway. A guy I went to high school with was crippled when a car hit him after he stopped to help someone change a tire. Just drive to a safe place. If it really is that sketchy of an area, I wouldn't want to get out to use Fix-a-Flat either. If you ruin a tire or even a rim, so be it. Your safety is the top priority.
I have had to make that decision twice... Once when I had a flat in my old Benz. I just drove to the next exit, found a service station, and pulled in. No drama. The other time, I had a blowout on the highway in a class A motorhome. I pulled onto the shoulder to take a look, then decided to continue (on the shoulder) until I got to an area where I could pull further off the road. The tire and rim were toast, but that was just from the initial blowout, anyway.